Registration required | Attendance in-person

Description: Cytoscape is widely used open-source tools for the analysis and visualization of omics networked data e.g., proteomics, transcriptomics, metabolomics. Its algorithms and complementary apps allow for the exploration of complex interactions between experimentally generated molecules, and the subsequent prediction of functions and pathways. This introductory session will provide an overview on how to use Cytoscape and the STRING app to analyze and functionally annotate a protein-protein interaction network generated from differentially expressed genes or differentially abundant proteins. During thesession, we will use a tutorial dataset that will be made available to all the registrants.

The goals of the session are:

• Learning how to load datasets and generate a protein interaction network using STRING.
• Understanding data visualization and learning how to navigate the network.
• Uploading molecule-associated data (e.g., fold changes, p-values) and visualizing it and other data annotations.
• Learning how to identify clusters and key nodes (hubs). 
• Learning how to do pathway analysis of the resulting network and clusters. 

Requisite:

Download and install Cytoscape 

Attendees to this workshop may also be interested in attending the workshops: Part 1 Overrepresentation Analysis, and Part 2 Gene Set Enrichment Analysis